mRNA drugs have recently come into the spotlight, revealing new therapeutic options in the times of COVID-19.
However, the effects of mRNA drugs are not at all limited to their ability to treat novel coronaviruses.
Small molecule drugs that target mRNA translation regulation are set to become the next decade's most promising drug opportunity.
mRNA Drugs in the Spotlight
mRNA vaccinations for COVID-19 are hugely significant, surpassing all historical records for vaccination development and deployment.
The COVID-19 vaccines have shown the world the potential for mRNA medicines to treat diseases effectively.
The rapid development and deployment of these mRNA vaccines are not only due to the large number of resources allotted to their purpose but the very process of mRNA drug creation.
mRNA vaccines can be created much more quickly and cheaply than traditional vaccinations.
mRNA drugs do not require a large quantity of a virus to be created (like convention vaccines), which means they can be developed much more safely.
The COVID-19 vaccinations quickly put mRNA drugs into the spotlight, but mRNA drugs' potential is far greater than effectively vaccinating against COVID-19.
mRNA Drugs are Revealing New Treatment Opportunities
mRNA is called by some in the industry 'the software of life' because it translates the genes of DNA into proteins that are involved in all bodily functions.
It's like code for your cells and organelles. mRNA drugs prompt proteins to be made inside the body and, with the right code, can be used for almost any application.
Conventional medicines were created by a process in which proteins were made by genetically engineering cells. This would be time-consuming and costly. mRNA drugs, essentially, cut out all of this costly and time-consuming work.
Not only does mRNA present a much more effective medicine development process, but it also has a much greater potential than conventional medicines.
Any protein target that can be imagined can, in theory, be harnessed by mRNA. This is because mRNA is suitable to encode for antibodies, antigens, cytokines, or any other type of protein.
mRNA drugs can be designed and optimized immunologically and pharmacologically, making them viable for a large range of potential applications.
Currently, mRNA drugs are already being developed to treat a large range of different diseases and illnesses.
For example, mRNA drugs are being used to target the neoepitopes in cancer tumours, with clinical trials showing signs of success.
mRNA therapies have direct biological targets that are outlined by specifically engineering a strand of mRNA.
Simply alerting the nucleobase code can change the impact of any mRNA drug. This means that mRNA drugs are more targeted and versatile than conventional treatments and have the potential to treat diseases that were previously considered undruggable.
mRNA drugs have transformed the therapeutics industry forever. As the case of COVID-19 has shown, mRNA drugs can be created much more quickly, cheaply, and effectively than any conventional vaccinations.
Not only are they quicker, cheaper, and safer in development, but mRNA drugs are unmatched in potential applications.